Persistence of Mumps Virus in Mouse L929 Cells

Morphological development of mumps virus in vero cells

Gamma Interferon-Treated Mouse L929 Cells

a site of macromolecular synthesis with the established IFN.y-induced inhibition of rickettsial growth. A method was developed to measure the syntheses of DNA, rRNA, and protein by R. prowazekii during a 2-h pulse-labeling period while the rickettsiae were growing within cultured host cells that had intact macromolecular synthesis. This method involved incubation of the rickettsia-infected cell...

Development of a New Live Attenuated Mumps Virus Vaccine in Human Deploid Cells

morphological development of mumps virus in vero cells

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Mumps virus-induced innate immune responses in mouse Sertoli and Leydig cells

Mumps virus (MuV) infection frequently causes orchitis and impairs male fertility. However, the mechanisms underlying the innate immune responses to MuV infection in the testis have yet to be investigated. This study showed that MuV induced innate immune responses in mouse Sertoli and Leydig cells through TLR2 and retinoic acid-inducible gene I (RIG-I) signaling, which result in the production ...